Headline : NIH-funded clinical trial links frequent anger to increased risk of heart disease

Read more from the original article on here at www.nih.gov.

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Findings demonstrate impairment of blood vessel function; may lead to heart attack, stroke.

Recurring feelings of anger may increase a person’s risk of developing heart disease by limiting the blood vessels’ ability to open, according to a new study supported by the National Institutes of Health. The study, published in the Journal of the American Heart Association (JAHA), shows for the first time that anger is linked to this vascular impairment — a precursor to the kind of long-term damage that can lead to heart attack and stroke.

“We’ve long suspected, based on observational studies, that anger can negatively affect the heart. This study in healthy adults helps fill a real knowledge gap and shows how this might occur,” said Laurie Friedman Donze, Ph.D., a psychologist and program officer in the Clinical Applications and Prevention Branch of the National Heart, Lung, and Blood Institute (NHLBI), which funded the study. “It also opens the door to promoting anger management interventions as a way to potentially help stave off heart disease, the leading cause of death in this country.”

While a brief spurt of occasional anger is normal and generally has a benign impact on the heart, it is recurring or frequent anger the researchers said raises concern. “If you’re a person who gets angry all the time, you’re having chronic injuries to your blood vessels,” said study leader Daichi Shimbo, M.D., a cardiologist at Columbia University Irving Medical Center in New York City. “It’s these chronic injuries over time that may eventually cause irreversible effects on vascular health and eventually increase your heart disease risk.”     For the randomized, controlled study, researchers recruited 280 healthy adults aged 18 to 73 years within the New York City area. The participants were free of cardiovascular disease and without risk factors such as history of hypertension, diabetes, and lipid imbalances, according to self-reported survey data. All participants were non-smokers, medication-free, and without a history of diagnosed mood disorders.  

Read more from the original article on here at www.nih.gov.

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