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Headline : TAR-200 monotherapy shows greater than 80% complete response rate in patients with high-risk non-muscle-invasive bladder cancer

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Tags : #tar200 #monotherapy #shows #greater #than #8025 #complete #response #rate #patients #highrisk #nonmuscleinvasive #bladder #cancer



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New data from Phase 2b SunRISe-1 study show rapid achievement of complete response (CR) with 98% achieving a CR within 12 weeks

TAR-200 provides durable CRs in patients with Bacillus Calmette-Guรฉrin (BCG)โ€“unresponsive high-risk nonโ€“muscle-invasive bladder cancer (NMIBC) with carcinoma in situ โ€“ a disease area with limited treatment options for patients

SAN ANTONIO, May 3, 2024 /PRNewswire/ -- Johnson & Johnson announced today updated results from Cohort 2 of the Phase 2b SunRISe-1 study evaluating the efficacy and safety of investigational TAR-200 monotherapy in patients with BCG-unresponsive high-risk nonโ€“muscle-invasive bladder cancer (HR-NMIBC) with carcinoma in situ, who are ineligible for, or decline, radical cystectomy. These data were featured today in a plenary session (Abstract #P2-01) at the 2024 American Urological Association Annual Meeting (AUA) taking place May 3-6, 2024, in San Antonio, Texas.

"The high complete response rate and durability of these responses observed in patients treated with TAR-200 underscores the potential of this treatment approach for patients with BCG-unresponsive HR-NMIBC," said Joseph Jacob,* M.D., M.S., Department of Urology, Upstate Medical University, presenting author. "These results address an area of high unmet need for bladder sparing therapies in this patient population."

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